Journal article icon

Journal article

Contrasting within- and between-host immune selection shapes Neisseria Opa repertoires

Abstract:

Pathogen evolution is influenced strongly by the host immune response. Previous studies of the effects of herd immunity on the population structure of directly transmitted, short-lived pathogens have primarily focused on the impact of competition for hosts. In contrast, for long-lived infections like HIV, theoretical work has focused on the mechanisms promoting antigenic variation within the host. In reality, successful transmission requires that pathogens balance both within- and between-hos...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1038/srep06554

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Role:
Author
Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific reports Journal website
Volume:
4
Pages:
6554
Chapter number:
ARTN 6554
Publication date:
2014-10-09
Acceptance date:
2014-09-08
DOI:
EISSN:
2045-2322
ISSN:
2045-2322
URN:
uuid:a85319a0-8b5d-4468-be64-f31520fdd673
Source identifiers:
486957
Local pid:
pubs:486957

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP