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Journal article

Quantitative ex vivo analysis of functional virus-specific CD8 T lymphocytes in the blood and genital tract of HIV-infected women.

Abstract:

BACKGROUND: CD8 T lymphocytes are important in HIV-1 control and mediate virus-specific immunity in the blood and genital tract. The induction and monitoring of mucosal CD8 cell responses will be an important component of HIV-1 vaccine trials, but information regarding the frequency, phenotype and function of genital tract CD8 cell responses is lacking. METHODS: Simultaneous blood and cervical cytobrush samples were obtained from 16 HIV-1-infected Kenyan sex workers. Epitope-specific CD8 T l...

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Publication status:
Published

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Journal:
AIDS (London, England) More from this journal
Volume:
17
Issue:
8
Pages:
1139-1144
Publication date:
2003-05-01
DOI:
EISSN:
1473-5571
ISSN:
0269-9370
Language:
English
Keywords:
Pubs id:
pubs:29697
UUID:
uuid:a850ed62-71b9-442d-8b62-f2271e21a644
Local pid:
pubs:29697
Source identifiers:
29697
Deposit date:
2012-12-19

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