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Journal article

Phenotypic analysis of human CD4+ T cells specific for immediate-early 63 protein of varicella-zoster virus.

Abstract:

Open reading frame 63 of varicella-zoster Virus (VZV) encodes an immediate early (IE) phosphoprotein (IE63) that is believed to be important for viral infectivity and establishing latency. Evidence suggests that VZV-specific T cells are crucial in the control of viral replication; however, data addressing the existence of IE63 protein-specific CD4+ T cells are limited. Using IFN-gamma immunosorbent assays, we identified high frequencies of responses to overlapping peptides spanning the IE63 p...

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Publication status:
Published

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Publisher copy:
10.1002/eji.200737648

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
Journal:
European journal of immunology More from this journal
Volume:
37
Issue:
12
Pages:
3393-3403
Publication date:
2007-12-01
DOI:
EISSN:
1521-4141
ISSN:
0014-2980

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