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Journal article

Caveolin-1 and lipid rafts in confluent BeWo trophoblasts: evidence for Rock-1 association with caveolin-1.

Abstract:

Lipid rafts are detergent-insoluble, low-density membrane domains that are rich in cholesterol and sphingolipids; caveolae are a subdomain of the biochemically defined glycolipid raft whose expression is associated with the protein caveolin-1. This protein associates with numerous signalling molecules, regulating their activity by holding them inactive. Human villous cytotrophoblasts contain caveolin-1, but levels reduce greatly during their differentiation into syncytiotrophoblast. Since cav...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Women's and Reproductive Health
Role:
Author
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Journal:
Placenta
Volume:
28
Issue:
2-3
Pages:
139-151
Publication date:
2007-01-01
DOI:
EISSN:
1532-3102
ISSN:
0143-4004
Source identifiers:
114248

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