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Chronic embedded cortico thalamic closed loop deep brain stimulation for the treatment of essential tremor

Abstract:

Deep brain stimulation (DBS) is an approved therapy for the treatment of medicallyrefractory and severe movement disorders. However, most existing neurostimulators can only apply continuous stimulation (open-loop DBS, OL-DBS), ignoring patient behavior and environmental factors, which consequently leads to an inefficient therapy, thus limiting the therapeutic window. Here, we established the feasibility of a self-adjusting therapeutic DBS (closed-loop DBS, CL-DBS), fully embedded in a chronic...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1126/scitranslmed.aay7680

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Division:
MPLS
Department:
Engineering Science
Role:
Author
More by this author
Division:
MPLS
Department:
Engineering Science
Role:
Author
Publisher:
American Association for the Advancement of Science
Journal:
Science Translational Medicine More from this journal
Volume:
12
Issue:
572
Article number:
eaay7680
Publication date:
2020-12-02
Acceptance date:
2020-08-25
DOI:
EISSN:
1946-6242
ISSN:
1946-6234
Language:
English
Keywords:
Pubs id:
1131251
Local pid:
pubs:1131251
Deposit date:
2020-09-09

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