- Abstract:
-
The importance of thyrotropin receptor (TSHR) agonist antibodies in the manifestations of Graves' disease (GD) is recognized. There are, however, no convincing reports of TSHR-specific T cells. We have previously cloned T cells specific for thyroglobulin and thyroid peroxidase (TPO) from GD lymphoid infiltrates and used autologous EBV-transformed B cell lines (EBVL) transfected with an expression vector encoding TPO to efficiently detect TPO-specific T cells. Here we used EBVL transfected wit...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1172/jci118034
-
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- Journal:
- The Journal of clinical investigation
- Volume:
- 96
- Issue:
- 1
- Pages:
- 30-37
- Publication date:
- 1995-07-05
- DOI:
- EISSN:
-
1558-8238
- ISSN:
-
0021-9738
- URN:
-
uuid:a82b2329-7dfe-4540-a8b7-b5488f7f9171
- Source identifiers:
-
481641
- Local pid:
- pubs:481641
- Copyright date:
- 1995
Journal article
Identification of thyroid stimulating hormone receptor-specific T cells in Graves' disease thyroid using autoantigen-transfected Epstein-Barr virus-transformed B cell lines.
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