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Using HTK for prolonged pancreas preservation prior to human islet isolation

Abstract:

Background: Histidine-tryptophan-ketoglutarate (HTK) has been established as an alternative to University-of-Wisconsin solution (UWS) for abdominal organ preservation, but data about HTK efficiency to preserve pancreata during prolonged cold ischemia time (CIT) are conflicting. In human islet transplantation, HTK provided similar isolation outcomes after short CIT. The present study aimed to investigate whether islets can be successfully isolated from HTK-preserved pancreata after prolonged C...

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Publisher copy:
10.1016/j.jss.2011.03.012

Authors


Caballero-Corbalán, J More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Surgical Sciences
Felldin, M More by this author
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Journal:
Journal of Surgical Research
Volume:
175
Issue:
1
Pages:
163-168
Publication date:
2012-06-01
DOI:
EISSN:
1095-8673
ISSN:
0022-4804
URN:
uuid:a8249d8d-d8f8-488e-90b4-c22f747a495b
Source identifiers:
330337
Local pid:
pubs:330337

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