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Journal article

Optimizing hepcidin measurement with a proficiency test framework and standardization improvement

Abstract:

Objectives Hepcidin measurement advances insights in pathophysiology, diagnosis, and treatment of iron disorders, but requires analytically sound and standardized measurement procedures (MPs). Recent development of a two-level secondary reference material (sRM) for hepcidin assays allows worldwide standardization. However, no proficiency testing (PT) schemes to ensure external quality assurance (EQA) exist and the absence of a high calibrator in the sRM set precludes optim...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1515/cclm-2020-0928

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author
ORCID:
0000-0001-5977-6602
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Name:
Medical Research Council
Grant:
4050630002
Publisher:
De Gruyter
Journal:
Clinical Chemistry and Laboratory Medicine More from this journal
Volume:
59
Issue:
2
Pages:
315–323
Publication date:
2020-10-01
Acceptance date:
2020-09-04
DOI:
EISSN:
1437-4331
ISSN:
1434-6621
Pmid:
33001847
Language:
English
Keywords:
Pubs id:
1137167
Local pid:
pubs:1137167
Deposit date:
2020-11-05

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