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Journal article

Toll-interacting protein modulates colitis susceptibility in mice

Abstract:

Background: The intestinal epithelium accommodates with a myriad of commensals to maintain immunological homeostasis, but the underlying mechanisms regulating epithelial responsiveness to flora-derived signals remain poorly understood. Herein, we sought to determine the role of the Toll/ interleukin (IL)-1 receptor regulator Toll-interacting protein (Tollip) in intestinal homeostasis. Methods: Colitis susceptibility was determined after oral dextran sulfate sodium (DSS) administration or by b...

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Publisher:
John Wiley and Sons Inc.
Journal:
Inflammatory Bowel Diseases More from this journal
Volume:
20
Issue:
4
Pages:
660-670
Publication date:
2014-01-01
DOI:
EISSN:
1536-4844
ISSN:
1078-0998
Language:
English
Keywords:
Pubs id:
pubs:464234
UUID:
uuid:a7fd6648-1cbe-44d1-900d-ef1b29430805
Local pid:
pubs:464234
Source identifiers:
464234
Deposit date:
2014-06-17

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