Enhanced brain extraction improves the accuracy of brain atrophy estimation.
BET (Brain Extraction Tool) is a widely used computer program to automatically separate brain from non-brain structures in MR images. This procedure is used in SIENAX and SIENA, which are robust approaches to quantifying brain volume (atrophy state) and volume change (atrophy rate), respectively. Occasionally, however, BET produces imperfect results (e.g., inclusion of non-brain structures). This is usually either ignored (if inaccuracies are small) or corrected by manual adjustment, with the...Expand abstract
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