- Abstract:
-
In genome-wide association studies (GWASs) of colorectal cancer, we have identified two genomic regions in which pairs of tagging-single nucleotide polymorphisms (tagSNPs) are associated with disease; these comprise chromosomes 1q41 (rs6691170, rs6687758) and 12q13.13 (rs7163702, rs11169552). We investigated these regions further, aiming to determine whether they contain more than one independent association signal and/or to identify the SNPs most strongly associated with disease. Genotyping ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 518.2kb)
-
- Publisher copy:
- 10.1093/hmg/ddr523
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- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Human molecular genetics Journal website
- Volume:
- 21
- Issue:
- 4
- Pages:
- 934-946
- Publication date:
- 2012-02-05
- DOI:
- EISSN:
-
1460-2083
- ISSN:
-
0964-6906
- URN:
-
uuid:a7fa476e-51e4-4877-bab8-ea889ffde17a
- Source identifiers:
-
272112
- Local pid:
- pubs:272112
- Language:
- English
- Keywords:
- Copyright holder:
- Spain et al.
- Copyright date:
- 2012
- Notes:
- Copyright © 2011 Spain et al. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Journal article
Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13.
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Cancer Research UK
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