Journal article
Refinement of the associations between risk of colorectal cancer and polymorphisms on chromosomes 1q41 and 12q13.13.
- Abstract:
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In genome-wide association studies (GWASs) of colorectal cancer, we have identified two genomic regions in which pairs of tagging-single nucleotide polymorphisms (tagSNPs) are associated with disease; these comprise chromosomes 1q41 (rs6691170, rs6687758) and 12q13.13 (rs7163702, rs11169552). We investigated these regions further, aiming to determine whether they contain more than one independent association signal and/or to identify the SNPs most strongly associated with disease. Genotyping ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
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- Files:
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(pdf, 518.2KB)
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- Publisher copy:
- 10.1093/hmg/ddr523
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Authors
Funding
Cancer Research UK
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Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Human molecular genetics Journal website
- Volume:
- 21
- Issue:
- 4
- Pages:
- 934-946
- Publication date:
- 2012-02-05
- DOI:
- EISSN:
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1460-2083
- ISSN:
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0964-6906
- URN:
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uuid:a7fa476e-51e4-4877-bab8-ea889ffde17a
- Source identifiers:
-
272112
- Local pid:
- pubs:272112
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright holder:
- Spain et al.
- Copyright date:
- 2012
- Notes:
- Copyright © 2011 Spain et al. Published by Oxford University Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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