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Thesis

The impact of macrophage inflammatory protein-3 alpha and other innate immune markers on susceptibility/resistance to HIV infection in the female genital tract mucosa using cellular and ex vivo tissue models

Subtitle:
MIP-3α in the endocervix in the context of HIV infection
Abstract:

The distinctive feature of the Human Immunodeficiency Virus (HIV) epidemic in the 21st century is the burden it places on women. Scientists believe that the best opportunities for successful interventions to prevent sexual HIV transmission lie in the initial stages of infection at the portal of entry, the genital tract (GT), which offers the greatest host advantages and viral vulnerabilities. However, understanding of the correlates of protection/vulnerability and innate immunity at the po...

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Department:
Nuffield Department of Clinical Medicine, University of Oxford
Role:
Supervisor
Department:
Department of Medicine, Imperial College London
Role:
Supervisor
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Grant:
HIVRT13-124
Funding agency for:
Project
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Grant:
B5Sibeko
Funding agency for:
Project
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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