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Multiscale stochastic reaction-diffusion modelling: application to actin dynamics in filopodia

Abstract:

Two multiscale (hybrid) stochastic reaction-diffusion models of actin dynamics in a filopodium are investigated. Both hybrid algorithms combine compartment-based and molecular-based stochastic reaction-diffusion models. The first hybrid model is based on the models previously developed in the literature. The second hybrid model is based on the application of recently developed two-regime method (TRM) to a fully molecular-based model which is also developed in this paper. The results of hybrid...

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Publication date:
2012-01-01
UUID:
uuid:a7dbce4d-8baa-4ceb-b937-ed5d4a1e68cf
Local pid:
oai:eprints.maths.ox.ac.uk:1665
Deposit date:
2013-02-10

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