Inferring microevolutionary patterns from allele-size frequency distributions of minisatellite loci: a worldwide study of the APOB 3' hypervariable region polymorphism.

Journal article

The availability of numerous population and molecular data makes the apolipoprotein B 3' hypervariable region (APOB 3' HVR) polymorphism ideal for a pilot study of the relationships between the allele-size frequency distributions (referred to as allele-size distributions) of minisatellite loci and the microevolutionary processes underlying their present-day polymorphism in human populations. In this paper, we present a worldwide APOB 3' HVR study, based on published and unpublished data, whic...

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Authors: Destro-Bisol, G; Capelli, C; Belledi, M

• Publication status: Published
• Journal: Human biology
• Volume: 72
• Issue: 5
• Pages: 733-751
• Publication date: 2000-10-01
• EISSN: 1534-6617
• ISSN: 0018-7143
• Language: English
• Keywords: Apolipoproteins B; Confounding Factors (Epidemiology); Complementarity Determining Regions; African Continental Ancestry Group; Heterozygote; Minisatellite Repeats; European Continental Ancestry Group; Gene Frequency; Asian Continental Ancestry Group; Mutation; Oceanic Ancestry Group; Biological Evolution; Genetic Variation; Polymorphism, Genetic; Models, Genetic; Pilot Projects; Emigration and Immigration; Phylogeny; Humans