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Journal article

IRF5 is a specific marker of inflammatory macrophages in vivo.

Abstract:

Macrophages are an integral part of the innate immune system and key players in pathogen clearance and tissue remodelling. Both functions are accomplished by a pivotal network of different macrophage subtypes, including proinflammatory M1 and anti-inflammatory M2 macrophages. Previously, our laboratory identified the transcription factor interferon regulatory factor 5 (IRF5) as the master regulator of the M1 macrophage polarisation. IRF5 was found to be highly expressed in human M1 compared t...

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Publication status:
Published

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Publisher copy:
10.1155/2013/245804

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Publisher:
Hindawi Publishing Corporation
Journal:
Mediators of inflammation
Volume:
2013
Pages:
245804
Publication date:
2013-01-01
DOI:
EISSN:
1466-1861
ISSN:
0962-9351
URN:
uuid:a7ccd1c4-3b28-43bd-87ce-9144df656af6
Source identifiers:
446771
Local pid:
pubs:446771

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