- Abstract:
-
The Brn-3a transcription factor has two distinct activation domains located, respectively, at the N-terminus and the C-terminus (coincident with the DNA binding POU domain) which differ in their effects on different target promoters. To analyze whether these regions could function when linked to a heterologous DNA binding domain, they were each linked to the GAL4 DNA binding domain. Here we show that the N-terminal domain constitutes a discrete activation domain which can function when linked...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/S1357-2725(97)00089-7
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- Journal:
- INTERNATIONAL JOURNAL OF BIOCHEMISTRY and CELL BIOLOGY
- Volume:
- 29
- Issue:
- 12
- Pages:
- 1493-1500
- Publication date:
- 1997-12-05
- DOI:
- ISSN:
-
1357-2725
- URN:
-
uuid:a7a38201-851b-4c0c-85e6-cf687d3d74e7
- Source identifiers:
-
114420
- Local pid:
- pubs:114420
- Language:
- English
- Keywords:
- Copyright date:
- 1997
Journal article
The two activation domains of the Brn-3a transcription factor have distinct functional properties
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