- Abstract:
- We conducted a trial of oral acetazolamide for the treatment of cryptococcal meningitis in 22 Thai adults with headache and an opening cerebrospinal fluid pressure of >/=200 mm H(2)0. The trial was terminated prematurely because patients who received acetazolamide developed significantly lower venous bicarbonate levels and higher chloride levels and had more-frequent serious adverse events than did subjects who received placebo.
- Publication status:
- Published
- Publisher copy:
- 10.1086/342299
-
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- Journal:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
- Volume:
- 35
- Issue:
- 6
- Pages:
- 769-772
- Publication date:
- 2002-09-05
- DOI:
- EISSN:
-
1537-6591
- ISSN:
-
1058-4838
- URN:
-
uuid:a79dc560-af06-4643-88c7-d06763994be2
- Source identifiers:
-
8990
- Local pid:
- pubs:8990
- Copyright date:
- 2002
Journal article
A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment of elevated intracranial pressure in cryptococcal meningitis.
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