Probing heteronuclear (15)N-(17)O and (13)C-(17)O connectivities and proximities by solid-state NMR spectroscopy.

Journal article

Heteronuclear solid-state magic-angle spinning (MAS) NMR experiments for probing (15)N-(17)O dipolar and J couplings are presented for [(2)H(NH(3)),1-(13)C,(15)N,(17)O(2)]glycine.(2)HCl and [(15)N(2),(17)O(2)]uracil. Two-dimensional (15)N-(17)O correlation spectra are obtained using the R(3)-HMQC experiment; for glycine.(2)HCl, the intensity of the resolved peaks for the CO and C-O(2)H (17)O resonances corresponds to the relative magnitude of the respective (15)N-(17)O dipolar couplings. (17)...

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Authors: Hung, I; Uldry, A; Becker-Baldus, J; Webber, A; Wong, A

• Publication status: Published
• Journal: Journal of the American Chemical Society
• Volume: 131
• Issue: 5
• Pages: 1820-1834
• Publication date: 2009-02-01
• DOI: 10.1021/ja805898d
• EISSN: 1520-5126
• ISSN: 0002-7863
• Language: English
• Keywords: Nuclear Magnetic Resonance, Biomolecular; Glycine; Isotope Labeling; Uracil; Carbon Isotopes; Hydrogen Bonding; Nitrogen Isotopes; Oxygen Isotopes; Models, Molecular