Journal article
The cardiac sympathetic co-transmitter neuropeptide Y is pro-arrhythmic following ST-elevation myocardial infarction despite beta-blockade
- Abstract:
-
AIMS:ST-elevation myocardial infarction is associated with high levels of cardiac sympathetic drive and release of the co-transmitter neuropeptide Y (NPY). We hypothesized that despite beta-blockade, NPY promotes arrhythmogenesis via ventricular myocyte receptors. METHODS AND RESULTS:In 78 patients treated with primary percutaneous coronary intervention, sustained ventricular tachycardia (VT) or fibrillation (VF) occurred in 6 (7.7%) within 48 h. These patients had significantly (P < 0.05)...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- European Heart Journal Journal website
- Volume:
- 41
- Issue:
- 23
- Pages:
- 2168-2179
- Publication date:
- 2019-12-13
- Acceptance date:
- 2019-11-12
- DOI:
- EISSN:
-
1522-9645
- ISSN:
-
0195-668X
- Pmid:
-
31834357
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1077950
- UUID:
-
uuid:a77d8660-557c-4a21-8028-78fb488a2b4f
- Local pid:
- pubs:1077950
- Source identifiers:
-
1077950
- Deposit date:
- 2019-12-16
Terms of use
- Copyright holder:
- Kalla et al.
- Copyright date:
- 2019
- Rights statement:
- © The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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