Journal article
Single arm NCRI phase II study of CHOP in combination with Ofatumumab in induction and maintenance for patients with newly diagnosed Richter’s syndrome
- Abstract:
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Background Transformation of B-cell chronic lymphocytic leukaemia (B-CLL) to diffuse large B cell lymphoma (DLBCL) (Richter’s syndrome (RS)) is a rare (2-15% of patients) but catastrophic complication of B-CLL. Dose-intense chemotherapy regimens investigated in small single institution trials, but with the exception of bone marrow transplantation for a minority of patients, little has improved the median overall survival of patients with RS beyond eight months. Patients ar...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
National Institute of Health Research
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Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Cancer Journal website
- Volume:
- 15
- Issue:
- 1
- Article number:
- 52
- Publication date:
- 2015-02-13
- Acceptance date:
- 2015-01-28
- DOI:
- EISSN:
-
1471-2407
- ISSN:
-
1471-2407
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:510418
- UUID:
-
uuid:a75d65d2-a154-4176-bbab-c589f937a80f
- Local pid:
- pubs:510418
- Source identifiers:
-
510418
- Deposit date:
- 2015-11-03
Terms of use
- Copyright holder:
- Eyre et al
- Copyright date:
- 2015
- Rights statement:
- Copyright © 2015 Eyre et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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