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The role of the gastrointestinal tract in toxigenic Clostridium tetani infection: a case-control study

Abstract:

Tetanus arises from wound contamination with Clostridium tetani, but approximately one fifth of patients have no discernable entry wound. Clostridium tetani is culturable from animal feces, suggesting the gastrointestinal tract could be an endogenous reservoir or direct-entry portal, but human data are lacking. In this study of 101 Vietnamese adults with tetanus and 29 hospitalized control subjects, admission stool samples were cultured for C. tetani. Anti-tetanus toxin antibodies were measur...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.4269/ajtmh.21-0146

Authors


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Name:
Wellcome Trust
Grant:
9226
Publisher:
American Society of Tropical Medicine and Hygiene
Journal:
American Journal of Tropical Medicine and Hygiene More from this journal
Volume:
105
Issue:
2
Pages:
494–497
Publication date:
2021-06-28
Acceptance date:
2021-03-29
DOI:
EISSN:
1476-1645
ISSN:
0002-9637
Pmid:
34181568
Language:
English
Keywords:
Pubs id:
1186199
Local pid:
pubs:1186199
Deposit date:
2021-07-16

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