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Estimating the false-negative test probability of SARS-CoV-2 by RT-PCR

Abstract:

Background
Reverse-transcription PCR (RT-PCR) assays are used to test for infection with the SARS-CoV-2 virus. RT-PCR tests are highly specific and the probability of false positives is low, but false negatives are possible depending on swab type and time since symptom onset.
Aim
To determine how the probability of obtaining a false-negative test in infected patients is affected by time since symptom onset and swab type.
Methods<...> Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Sub department:
Zoology
Role:
Author
ORCID:
0000-0002-9318-2581
Publisher:
European Centre for Disease Prevention and Control
Journal:
Eurosurveillance More from this journal
Volume:
25
Issue:
50
Article number:
2000568
Pages:
28-37
Publication date:
2020-12-17
Acceptance date:
2020-08-12
DOI:
EISSN:
1560-7917
ISSN:
1025-496X
Pmid:
33334398

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