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Statistical simplicity in long-term animal feeding studies of suspect carcinogens

Abstract:

The statistical interpretation of long-term animal carcinogenesis experiments seems complicated at first sight, because the early death of the treated animals can do two things. First, if it is early enough in the animal's lifespan, premature death may prevent the occurrence of a tumour that would have arisen had the animal lived on, thereby artificially diminishing the net tumour yield and suggesting (to any unwary person who merely looks at the percentage of animals that ever develop tumour...

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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
Journal:
Archives of Toxicology More from this journal
Volume:
49
Issue:
Suppl. 5
Pages:
254-255
Publication date:
1982-01-01
ISSN:
0340-5761
Language:
English
Pubs id:
pubs:79956
UUID:
uuid:a750b2f6-8774-4ff3-97a1-1ddf7b0159ae
Local pid:
pubs:79956
Source identifiers:
79956
Deposit date:
2013-02-20

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