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The haematological consequences of plasmodium vivax malaria after chloroquine treatment with and without primaquine: a WorldWide Antimalarial Resistance Network systematic review and individual patient data meta-analysis

Abstract:
Background Malaria causes a reduction in haemoglobin that is compounded by primaquine, particularly in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency. The aim of this study was to determine the relative contributions to red cell loss of malaria and primaquine in patients with uncomplicated Plasmodium vivax.

Methods A systematic review identified P. vivax efficacy studies of chloroquine with or without primaquine published between... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1186/s12916-019-1386-6

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0002-3359-5632
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More from this funder
Name:
Wellcome Trust
Grant:
200909/Z/16/Z
Publisher:
BioMed Central
Journal:
BMC Medicine More from this journal
Volume:
17
Article number:
151
Publication date:
2019-08-01
Acceptance date:
2019-07-09
DOI:
EISSN:
1741-7015
Language:
English
Pubs id:
pubs:1037044
UUID:
uuid:a746ba1c-bd4e-485e-8ca2-7f77be2be852
Local pid:
pubs:1037044
Source identifiers:
1037044
Deposit date:
2019-08-02

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