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Oscillations in a maturation model of blood cell production

Abstract:

We present a mathematical model of blood cell production which describes both the development of cells through the cell cycle, and the maturation of these cells as they differentiate to form the various mature blood cell types. The model differs from earlier similar ones by considering primitive stem cells as a separate population from the differentiating cells, and this formulation removes an apparent inconsistency in these earlier models. Three different controls are included in the model: ...

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Publication status:
Published

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Publisher copy:
10.1137/050648055
Journal:
SIAM JOURNAL ON APPLIED MATHEMATICS More from this journal
Volume:
66
Issue:
6
Pages:
2027-2048
Publication date:
2006-01-01
DOI:
EISSN:
1095-712X
ISSN:
0036-1399
Language:
English
Keywords:
Pubs id:
pubs:189280
UUID:
uuid:a72cd55d-ab0e-45b4-b0cb-dd8d487ea332
Local pid:
pubs:189280
Source identifiers:
189280
Deposit date:
2012-12-19

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