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Journal article : Review

A decade of blood biomarkers for Alzheimer's disease research: an evolving field, improving study designs, and the challenge of replication

Abstract:

Blood-based biomarkers represent a less invasive and potentially cheaper approach for aiding Alzheimer’s disease (AD) detection compared with cerebrospinal fluid and some neuroimaging biomarkers. Acknowledging that many in the field have made great progress, here we review some of the work that our group has pursued to identify and validate blood-based proteomic biomarkers through both case control and AD pathology endophenotype-based approaches. Our focus is primarily to identify a minimally...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.3233/JAD-170531

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Role:
Author
ORCID:
0000-0003-1752-0419
More by this author
Division:
MSD
Sub department:
Psychiatry
Role:
Author
ORCID:
0000-0003-0506-7813
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Name:
Medical Research Council
Grant:
MR/L023784/1
MR/L023784/2
Publisher:
IOS Press
Journal:
Journal of Alzheimer's Disease More from this journal
Volume:
62
Issue:
3
Pages:
1181-1198
Publication date:
2018-03-13
Acceptance date:
2017-09-11
DOI:
EISSN:
1875-8908
ISSN:
1387-2877
Pmid:
29562526
Language:
English
Keywords:
Subtype:
Review
Pubs id:
831148
Local pid:
pubs:831148
Deposit date:
2020-03-20

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