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A competitive radioimmunoassay using a monoclonal antibody to detect the factor X activator of Russell's viper venom.

Abstract:

A radioimmunoassay (RIA) has been developed for the detection of Russell's viper venom in body fluids. This is a competitive binding technique using a monoclonal antibody directed against the factor X activator of Russell's viper venom. The sensitivity of the test in urine was 4 ng/ml, in 0.1% bovine serum albumin-phosphate buffered saline it was 20 ng/ml and in serum it was 5 micrograms/ml. This was adequate to detect venom in the serum of four patients bitten by Russell's viper. Urine from ...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
CCMP
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Toxicon : official journal of the International Society on Toxinology More from this journal
Volume:
25
Issue:
7
Pages:
721-729
Publication date:
1987-01-01
DOI:
EISSN:
1879-3150
ISSN:
0041-0101
Language:
English
Keywords:
Pubs id:
pubs:3258
UUID:
uuid:a7276425-de3e-4b1b-8c27-ad1569295712
Local pid:
pubs:3258
Source identifiers:
3258
Deposit date:
2012-12-19

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