Journal article
Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke.
- Abstract:
-
Neural stem cells (NSCs) in the adult rat subventricular zone (SVZ) generate new striatal neurons during several months after ischemic stroke. Whether the microglial response associated with ischemic injury extends into SVZ and influences neuroblast production is unknown. Here, we demonstrate increased numbers of activated microglia in ipsilateral SVZ concomitant with neuroblast migration into the striatum at 2, 6, and 16 weeks, with maximum at 6 weeks, following 2 h middle cerebral artery oc...
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- Publication status:
- Published
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- Publisher copy:
- 10.1002/glia.20810
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Bibliographic Details
- Journal:
- Glia
- Volume:
- 57
- Issue:
- 8
- Pages:
- 835-849
- Publication date:
- 2009-06-01
- DOI:
- EISSN:
-
1098-1136
- ISSN:
-
0894-1491
- Source identifiers:
-
246560
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:246560
- UUID:
-
uuid:a724bfa6-05c2-4e23-912d-f4c6f6c84f5d
- Local pid:
- pubs:246560
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2009
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