Journal article
Excessive synchronization of basal ganglia neurons at 20 Hz slows movement in Parkinson's disease.
- Abstract:
-
Excessive synchronization of neuronal activity at around 20 Hz is a common finding in the basal ganglia of patients with untreated Parkinson's disease (PD). Correlative evidence suggests, but does not prove, that this spontaneous activity may contribute to slowness of movement in this condition. Here we investigate whether externally imposed synchronization through direct stimulation of the region of the subthalamic nucleus at 20 Hz can slow motor performance in a simple unimanual tapping tas...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/j.expneurol.2007.01.027
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Authors
Bibliographic Details
- Journal:
- Experimental neurology
- Volume:
- 205
- Issue:
- 1
- Pages:
- 214-221
- Publication date:
- 2007-05-01
- DOI:
- EISSN:
-
1090-2430
- ISSN:
-
0014-4886
- Source identifiers:
-
368912
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:368912
- UUID:
-
uuid:a71d601b-b915-4314-b2bc-6c487c38b925
- Local pid:
- pubs:368912
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2007
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