Journal article icon

Journal article

Excessive synchronization of basal ganglia neurons at 20 Hz slows movement in Parkinson's disease.

Abstract:

Excessive synchronization of neuronal activity at around 20 Hz is a common finding in the basal ganglia of patients with untreated Parkinson's disease (PD). Correlative evidence suggests, but does not prove, that this spontaneous activity may contribute to slowness of movement in this condition. Here we investigate whether externally imposed synchronization through direct stimulation of the region of the subthalamic nucleus at 20 Hz can slow motor performance in a simple unimanual tapping tas...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Expand authors...
Journal:
Experimental neurology
Volume:
205
Issue:
1
Pages:
214-221
Publication date:
2007-05-05
DOI:
EISSN:
1090-2430
ISSN:
0014-4886
URN:
uuid:a71d601b-b915-4314-b2bc-6c487c38b925
Source identifiers:
368912
Local pid:
pubs:368912

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP