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Journal article

Comparison of the immunogenicity and protection against bovine tuberculosis following immunization by BCG-priming and boosting with adenovirus or protein based vaccines.

Abstract:

There is a requirement for vaccines or vaccination strategies that confer better protection against TB than the current live attenuated Mycobacterium bovis Bacillus Calmette-Guerin (BCG) vaccine for use in cattle. Boosting with recombinant viral vectors expressing mycobacterial proteins, such as Ag85A, has shown a degree of promise as a strategy for improving on the protection afforded by BCG. Experiments in small animal models have indicated that broadening the immune response to include myc...

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Publication status:
Published

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Journal:
Vaccine More from this journal
Volume:
32
Issue:
11
Pages:
1304-1310
Publication date:
2014-03-01
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
Language:
English
Keywords:
Pubs id:
pubs:443408
UUID:
uuid:a71c72b4-63e0-49aa-b814-200da6d5c2cf
Local pid:
pubs:443408
Source identifiers:
443408
Deposit date:
2014-02-08

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