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The concept of a random coil. Residual structure in peptides and denatured proteins.

Abstract:

Non-native states of proteins are of increasing interest because of their relevance to issues such as protein folding, translocation and stability. A framework for interpreting the wealth of experimental data for non-native states emerging from rapid advances in experimental techniques involves comparison with a "random coll' state, which possesses no structure except that inherent in the local interactions. We review here the concept of a random coil, from its global to its local properties....

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Inorganic Chemistry
Fiebig, KM More by this author
Schwalbe, H More by this author
Dobson, CM More by this author
Journal:
Folding and design
Volume:
1
Issue:
5
Pages:
R95-106
Publication date:
1996
DOI:
ISSN:
1359-0278
URN:
uuid:a71a6505-67f7-4539-8117-26e1cf1298b7
Source identifiers:
36034
Local pid:
pubs:36034

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