Journal article
SCOTTI: Efficient reconstruction of transmission within outbreaks with the structured coalescent
- Abstract:
-
Exploiting pathogen genomes to reconstruct transmission represents a powerful tool in the fight against infectious disease. However, their interpretation rests on a number of simplifying assumptions that regularly ignore important complexities of real data, in particular within-host evolution and non-sampled patients. Here we propose a new approach to transmission inference called SCOTTI (Structured COalescent Transmission Tree Inference). This method is based on a statistical framework that ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Funding
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS Computational Biology Journal website
- Volume:
- 12
- Issue:
- 9
- Article number:
- e1005130
- Publication date:
- 2016-09-28
- Acceptance date:
- 2016-09-05
- DOI:
- ISSN:
-
1553-7358
- Source identifiers:
-
646560
Item Description
- Pubs id:
-
pubs:646560
- UUID:
-
uuid:a71787b2-b4d4-4a55-8991-14288ab22ff4
- Local pid:
- pubs:646560
- Deposit date:
- 2016-09-29
Terms of use
- Copyright holder:
- De Maio et al
- Copyright date:
- 2016
- Notes:
- Copyright © 2016 De Maio et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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