Journal article icon

Journal article

Cellular immunity induced by the recombinant Plasmodium falciparum malaria vaccine, RTS,S/AS02, in semi-immune adults in The Gambia.

Abstract:

Vaccination of malaria-naive humans with recombinant RTS,S/AS02, which includes the C-terminus of the circumsporozoite protein (CS), has been shown to induce strong T cell responses to both the whole protein antigen and to peptides from CS. Here we show that strong T cell responses were also observed in a semi-immune population in The Gambia, West Africa. In a Phase I study, 20 adult male volunteers, lifelong residents in a malaria-endemic region, were given three doses of RTS,S/AS02 at 0, 1 ...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Journal:
Clinical and experimental immunology More from this journal
Volume:
135
Issue:
2
Pages:
286-293
Publication date:
2004-02-01
DOI:
EISSN:
1365-2249
ISSN:
0009-9104

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP