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Journal article

Clinical characteristics of subjects with a missense mutation in glucokinase.

Abstract:

The clinical characteristics of subjects with a missense glucokinase mutation, gly299-->arg, were studied in a large pedigree, BX, initially characterized by some members having Maturity Onset Diabetes of the Young (MODY). Glucose tolerance, beta cell function and insulin sensitivity were measured with Homeostasis Model Assessment (HOMA) and with a 'Continuous Infusion of Glucose with Model Assessment' (CIGMA) test. Diabetic complications were clinically assessed. Subjects with glucokinase...

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Publication status:
Published

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Authors


Hattersley, AT More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
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Journal:
Diabetic medicine : a journal of the British Diabetic Association
Volume:
12
Issue:
3
Pages:
209-217
Publication date:
1995-03-05
DOI:
EISSN:
1464-5491
ISSN:
0742-3071
URN:
uuid:a6f20909-8308-4a5e-a5f4-92f1b8af7cef
Source identifiers:
35689
Local pid:
pubs:35689

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