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A systematic evaluation of expression of HERV-W elements; influence of genomic context, viral structure and orientation.

Abstract:

BACKGROUND: One member of the W family of human endogenous retroviruses (HERV) appears to have been functionally adopted by the human host. Nevertheless, a highly diversified and regulated transcription from a range of HERV-W elements has been observed in human tissues and cells. Aberrant expression of members of this family has also been associated with human disease such as multiple sclerosis (MS) and schizophrenia. It is not known whether this broad expression of HERV-W elements represents...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/1471-2164-12-22
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Name:
Swedish Research Council
Grant:
61X-20047
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Name:
Stanley Medical Research Institute
Publisher:
BioMed Central
Journal:
BMC genomics More from this journal
Volume:
12
Issue:
1
Pages:
22
Publication date:
2011-01-01
DOI:
EISSN:
1471-2164
ISSN:
1471-2164
Language:
English
Keywords:
UUID:
uuid:a6e4752c-131b-48d2-af5a-76563a3d0d07
Local pid:
pubs:344388
Source identifiers:
344388
Deposit date:
2013-11-16

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