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Thesis

Improved methods for serial femtosecond crystallography reduction

Abstract:

X-ray free electron lasers (XFELs) are a young technology which alleviates a number of issues, including radiation damage, which remain problematic in conventional macromolecular X-ray crystallography. As it turned out, existing methods had been optimised for synchrotron-based rotation data and coped poorly with snapshot XFEL diffraction images. In the first four results chapters, I present algorithms developed in my efforts to contribute to improved data reduction for XFEL analysis. In or...

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Department:
University of Oxford
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Department:
University of Oxford
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Supervisor
Department:
Diamond Light Source Ltd.
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Grant:
075491/04
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Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford

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