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Journal article

The utrophin and dystrophin genes share similarities in genomic structure.

Abstract:

Utrophin and dystrophin are highly homologous proteins which are reciprocally expressed in DMD (Duchenne muscular dystrophy) muscle. The remarkable similarity of these proteins suggests that they may play a similar cellular role in some circumstances; if this were the case then utrophin may be capable of replacing dystrophin in DMD patients. In this paper we show that the genomic structure of the utrophin gene is similar to the dystrophin gene, further exemplifying the relatedness of the two ...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/2.11.1765

Authors


Tinsley, JM More by this author
Campbell, L More by this author
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Journal:
Human molecular genetics
Volume:
2
Issue:
11
Pages:
1765-1772
Publication date:
1993-11-05
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
URN:
uuid:a69e2a93-c07e-4985-b2f8-7553d36c984d
Source identifiers:
35827
Local pid:
pubs:35827

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