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Adult attention-deficit hyperactivity disorder is associated with alterations in circadian rhythms at the behavioural, endocrine and molecular levels.

Abstract:

Attention-deficit hyperactivity disorder (ADHD) in adults is associated with impaired sleep, and it has been postulated that this impairment may contribute to the psychopathology of this common condition. One key driver of sleep/wake cycles is the circadian system, which at the molecular level consists of a series of transcriptional feedback loops of clock genes, which in turn produce endocrine, physiological and behavioural outputs with a near 24 h periodicity. We set out to examine circadia...

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Publication status:
Published

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Publisher copy:
10.1038/mp.2011.149

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Coogan, AN More by this author
Siddiqui, A More by this author
Journal:
Molecular psychiatry
Volume:
17
Issue:
10
Pages:
988-995
Publication date:
2012-10-05
DOI:
EISSN:
1476-5578
ISSN:
1359-4184
URN:
uuid:a69df868-47be-4436-a4b1-70212e3076b7
Source identifiers:
491885
Local pid:
pubs:491885

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