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The impact of trial characteristics on premature discontinuation of antipsychotics in schizophrenia

Abstract:

Patient dropout is common in mental health trials. It is important to understand why patients drop out from trials, so that measures can be taken to minimize its occurrence. This research sought to identify trial characteristics that have an impact on premature discontinuation in antipsychotic trials for schizophrenia. Methods: Poisson regression analysis was applied with dropout rate per patient-week as the dependent variable and trial characteristics as independent variables. Multinomial lo...

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Authors


Spineli, LM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Higgins, JPT More by this author
Salanti, G More by this author
Journal:
European Neuropsychopharmacology
Volume:
23
Issue:
9
Pages:
1010-1016
Publication date:
2013-09-05
DOI:
EISSN:
1873-7862
ISSN:
0924-977X
URN:
uuid:a694eef0-d6e3-4ccd-9409-ef3e504f4fc6
Source identifiers:
454701
Local pid:
pubs:454701

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