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Cells cultured from the growing tip of red deer antler express alkaline phosphatase and proliferate in response to insulin-like growth factor-I.

Abstract:

Deer antler growth provides a unique natural model of rapid and complete bone regeneration. In this study, the distal antler tips of male red deer (Cervus elaphus) were collected post-mortem during the annual growth period (April-August), and an in vitro system established for the culture of cells from three regions; the inner layer of the perichondrium, the reserve mesenchyme and the cartilage zone. Alkaline phosphatase (ALP) expression by cultured cells, as demonstrated by enzyme histochemi...

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Publication status:
Published

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Publisher copy:
10.1677/joe.0.143r009

Authors


Oyajobi, BO More by this author
Oreffo, RO More by this author
Russell, RG More by this author
Journal:
The Journal of endocrinology
Volume:
143
Issue:
2
Pages:
R9-16
Publication date:
1994-11-05
DOI:
EISSN:
1479-6805
ISSN:
0022-0795
URN:
uuid:a68f05bc-dff6-4658-b20f-b83c15a2887a
Source identifiers:
108961
Local pid:
pubs:108961

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