- Abstract:
-
Preventing viral induced liver disease begins with an understanding 1 of the host factors that define susceptibility to infection. Hepatitis C Virus (HCV) is a global health issue with an estimated 170 million infected individuals at risk of developing liver disease including fibrosis and hepatocellular carcinoma. The liver is the major reservoir supporting HCV replication and this hepatocellular tropism is defined by HCV engagement of cellular entry receptors. Hepatocytes are polarised in vi...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted manuscipt
- Files:
-
-
(pdf, 2.2MB)
-
- Publisher copy:
- 10.1099/jgv.0.000689
-
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- Publisher:
- Microbiology Society Publisher's website
- Journal:
- Journal of General Virology Journal website
- Volume:
- 98
- Pages:
- 405-412
- Publication date:
- 2017-03-05
- Acceptance date:
- 2016-12-15
- DOI:
- EISSN:
-
1465-2099
- ISSN:
-
0022-1317
- Pubs id:
-
pubs:673502
- URN:
-
uri:a680ece5-3baf-4a9e-8aef-b467771d14f0
- UUID:
-
uuid:a680ece5-3baf-4a9e-8aef-b467771d14f0
- Local pid:
- pubs:673502
- Language:
- English
- Copyright holder:
- McKeating et al
- Copyright date:
- 2017
- Notes:
- © 2017 The Authors. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
Journal article
TNF superfamily members promote hepatitis C virus entry via an NF-κB and myosin light chain kinase dependent pathway.
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