Journal article
TNF superfamily members promote hepatitis C virus entry via an NF-κB and myosin light chain kinase dependent pathway
- Abstract:
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Preventing virally induced liver disease begins with an understanding of the host factors that define susceptibility to infection. Hepatitis C virus (HCV) is a global health issue, with an estimated 170 million infected individuals at risk of developing liver disease including fibrosis and hepatocellular carcinoma. The liver is the major reservoir supporting HCV replication and this hepatocellular tropism is defined by HCV engagement of cellular entry receptors. Hepatocytes are polarized in v...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 2.2MB)
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- Publisher copy:
- 10.1099/jgv.0.000689
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Authors
Funding
Bibliographic Details
- Publisher:
- Microbiology Society Publisher's website
- Journal:
- Journal of General Virology Journal website
- Volume:
- 98
- Issue:
- 3
- Pages:
- 405-412
- Publication date:
- 2017-03-01
- Acceptance date:
- 2016-12-15
- DOI:
- EISSN:
-
1465-2099
- ISSN:
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0022-1317
- Source identifiers:
-
673502
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:673502
- UUID:
-
uuid:a680ece5-3baf-4a9e-8aef-b467771d14f0
- Local pid:
- pubs:673502
- Deposit date:
- 2017-01-29
Terms of use
- Copyright holder:
- Fletcher et al
- Copyright date:
- 2017
- Rights statement:
- © 2017 The Authors. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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