Journal article icon

Journal article

Drosophila Ana1 is required for centrosome assembly and centriole elongation

Abstract:

Centrioles organise centrosomes and cilia and these organelles have an important role in many cell processes. In flies, the centriole protein Ana1 is required for the assembly of functional centrosomes and cilia. It has recently been shown that Cep135/Bld10 initially recruits Ana1 to newly formed centrioles and Ana1 then recruits Asl/Cep152 to promote the conversion of these centrioles to centrosomes. Here we show that ana1 mutants lack detectable centrosomes in vivo, that Ana1 is irreversibl...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

Actions


Access Document


Files:
Publisher copy:
10.1242/jcs.186460

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Expand authors...
More from this funder
Funding agency for:
Saurya, S
More from this funder
Funding agency for:
Roque, H
More from this funder
Funding agency for:
Novak, ZA
More from this funder
Funding agency for:
Wainman, A
More from this funder
Funding agency for:
Aydogan, MG
Expand funders...
Publisher:
Company of Biologists Publisher's website
Journal:
Journal of Cell Science Journal website
Volume:
129
Issue:
13
Pages:
2514-2525
Publication date:
2016-07-01
DOI:
EISSN:
1477-9137
ISSN:
0021-9533
URN:
uuid:a66d09c9-2791-42b7-837b-b0e6eda6bd07
Source identifiers:
623172
Local pid:
pubs:623172

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP