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Jekyll and Hyde: the transformation of HLA-B27.

Abstract:
HLA-B27 can adopt a homodimeric form. In spondyloarthritis, such aberrant expression of B27 may override a tissue-specific inhibition of major histocompatibility complex (MHC) class I-dependent events, leading to inflammation and fibrosis.
Publication status:
Published

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Authors


Edwards, JC More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS, Experimental Medicine Division
Archer, JR More by this author
Journal:
Immunology today
Volume:
21
Issue:
6
Pages:
256-260
Publication date:
2000-06-05
DOI:
ISSN:
0167-5699
URN:
uuid:a65e659f-67e4-4930-8af2-f2db600f1fd0
Source identifiers:
84648
Local pid:
pubs:84648

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