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Jekyll and Hyde: the transformation of HLA-B27.

Abstract:
HLA-B27 can adopt a homodimeric form. In spondyloarthritis, such aberrant expression of B27 may override a tissue-specific inhibition of major histocompatibility complex (MHC) class I-dependent events, leading to inflammation and fibrosis.
Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Immunology today
Volume:
21
Issue:
6
Pages:
256-260
Publication date:
2000-06-01
DOI:
ISSN:
0167-5699
Source identifiers:
84648

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