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Journal article

The Interleukin-23 / Interleukin-17 axis in intestinal inflammation.

Abstract:

Although the precise aetiology of inflammatory bowel disease (IBD) remains unclear, recent discoveries have led to an improved understanding of disease pathogenesis. Whilst these findings have underscored the central role of innate and adaptive immune responses in intestinal inflammation, they have also precipitated a paradigm shift in the key cytokine pathways that drive disease. The prevailing dogma that IBD was mediated by interleukin (IL)-12-driven T-helper (Th)1 CD4 T cell responses towa...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Journal of internal medicine
Volume:
263
Issue:
6
Pages:
584-590
Publication date:
2008-06-05
DOI:
EISSN:
1365-2796
ISSN:
0954-6820
URN:
uuid:a65d831a-edca-4038-a908-4cffc730f227
Source identifiers:
56326
Local pid:
pubs:56326

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