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Journal article

Inherited genetic variants associated with melanoma BRAF/NRAS subtypes

Abstract:

BRAF and NRAS mutations arise early in melanoma development, but their associations with low-penetrance melanoma susceptibility loci remain unknown. In the Genes, Environment and Melanoma Study, 1,223 European-origin participants had their incident invasive primary melanomas screened for BRAF/NRAS mutations and germline DNA genotyped for 47 single-nucleotide polymorphisms identified as low-penetrant melanoma-risk variants. We used multinomial logistic regression to simultaneously examine each...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1016/j.jid.2018.04.025

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Publisher:
Elsevier Publisher's website
Journal:
Journal of investigative dermatology Journal website
Volume:
138
Issue:
11
Pages:
2398-2404
Publication date:
2018-07-04
Acceptance date:
2018-04-08
DOI:
EISSN:
1523-1747
ISSN:
0022-202X
Pubs id:
pubs:853590
URN:
uri:a63ee812-2945-4209-843d-6bfc839d19a3
UUID:
uuid:a63ee812-2945-4209-843d-6bfc839d19a3
Local pid:
pubs:853590
Language:
English
Keywords:

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