Journal article

Nprl3 is required for normal development of the cardiovascular system

Abstract:: C16orf35 is a conserved and widely expressed gene lying adjacent to the human α-globin cluster in all vertebrate species. In-depth sequence analysis shows that C16orf35 (now called NPRL3) is an orthologue of the yeast gene Npr3 (nitrogen permease regulator 3) and, furthermore, is a paralogue of its protein partner Npr2. The yeast Npr2/3 dimeric protein complex senses amino acid starvation and appropriately adjusts cell metabolism via the TOR pathway. Here we have analysed a mouse model in whi...
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APA Style

Kowalczyk, M. S., Hughes, J., Babbs, C., Sanchez-Pulido, L., Szumska, D., Sharpe, J., Sloane-Stanley, J., Morriss-Kay, G., Smoot, L., Roberts, A., Watkins, H., Bhattacharya, S., Gibbons, R., Ponting, C., Wood, W., & Higgs, D. R. (2012). Nprl3 is required for normal development of the cardiovascular system. Mammalian Genome, 23(7-8), 404–415.

MLA Style

Kowalczyk, M. S., et al. “Nprl3 Is Required for Normal Development of the Cardiovascular System.” Mammalian Genome, vol. 23, no. 7-8, 2012, pp. 404–15.

Chicago Style

Kowalczyk, MS, J Hughes, C Babbs, L Sanchez-Pulido, D Szumska, J Sharpe, J Sloane-Stanley, et al. 2012. “Nprl3 Is Required for Normal Development of the Cardiovascular System.” Mammalian Genome 23 (7-8): 404–15.
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Publisher copy:: 10.1007/s00335-012-9398-y

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+ Kowalczyk, MS More by this author

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+ Hughes, J More by this author

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University of Oxford

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MSD

Department:

RDM

Sub department:

Weatherall Insti. of Molecular Medicine

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Author

+ Babbs, C More by this author

Role:

Author

+ Sanchez-Pulido, L More by this author

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Author

+ Szumska, D More by this author

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Bibliographic Details

Journal:: Mammalian Genome More from this journal
Volume:: 23
Issue:: 7-8
Pages:: 404-415
Publication date:: 2012-08-01
DOI:: 10.1007/s00335-012-9398-y
EISSN:: 1432-1777
ISSN:: 0938-8990

Item Description

Language:: English
Pubs id:: pubs:350092
UUID:: uuid:a601f36a-0e17-4969-989c-dbaa7d3a5d29
Local pid:: pubs:350092
Source identifiers:: 350092
Deposit date:: 2013-11-16

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Copyright date:: 2012

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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