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The impact of diabetes mellitus on coronary artery disease: new therapeutic approaches.

Abstract:

Patients with diabetes mellitus (DM) type 2 have a high prevalence of coronary artery disease (CAD), as diabetes is implicated in the formation of atherosclerotic plaque. Hyperglycemia, elevated free fatty acid, increased amount of circulating end-glucosylated serum products and insulin resistance are the main mechanisms involved in the accelerated atherosclerotic process observed in type 2 DM patients. Novel treatments have been proposed to prevent and treat CAD in patients with diabetes, ma...

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Publisher copy:
10.2174/138161209788453185

Authors


Tousoulis, D More by this author
Kampoli, AM More by this author
Papageorgiou, N More by this author
Papaoikonomou, S More by this author
Antoniades, C More by this author
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Journal:
Current pharmaceutical design
Volume:
15
Issue:
17
Pages:
2037-2048
Publication date:
2009
DOI:
EISSN:
1873-4286
ISSN:
1381-6128
URN:
uuid:a5f315f0-5701-44ec-8842-a3136e30f4c0
Source identifiers:
223282
Local pid:
pubs:223282

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