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DNA hairpins: fuel for autonomous DNA devices.

Abstract:

We present a study of the hybridization of complementary DNA hairpin loops, with particular reference to their use as fuel for autonomous DNA devices. The rate of spontaneous hybridization between complementary hairpins can be reduced by increasing the neck length or decreasing the loop length. Hairpins with larger loops rapidly form long-lived kissed complexes. Hairpin loops may be opened by strand displacement using an opening strand that contains the same sequence as half of the neck and a...

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Publication status:
Published

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Publisher copy:
10.1529/biophysj.106.084681

Authors


Lubrich, D More by this author
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Institution:
University of Oxford
Department:
Oxford, MPLS, Physics, Condensed Matter Physics
Journal:
Biophysical journal
Volume:
91
Issue:
8
Pages:
2966-2975
Publication date:
2006-10-05
DOI:
EISSN:
1542-0086
ISSN:
0006-3495
URN:
uuid:a5e6b949-54cf-48a6-8e8b-8e8db3aa0c58
Source identifiers:
13643
Local pid:
pubs:13643

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