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Thesis

Biophysical studies of cytokine receptor interactions

Abstract:

The IL-6 family of cytokines includes IL-6, ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), oncostatin M (OSM), cardiotrophin-1, and IL-11. Functioning in a pleiotropic and redundant manner, these cytokines play an important role in the regulation of complex cellular processes such as gene activation, proliferation and differentiation, by signalling through homo- or heterodimers of gp130.

This thesis describes the characterization of the interactions between t...

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Institution:
University of Oxford
Department:
Faculty of Biological Sciences
Role:
Author

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Role:
Supervisor
Publication date:
2000
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Barcode:
603838812
URN:
uuid:a5dbcc9a-b73a-495a-8cf6-60ef064da0da
Local pid:
td:603838812
Language:
English
Subjects:

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