Biophysical studies of cytokine receptor interactions
The IL-6 family of cytokines includes IL-6, ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), oncostatin M (OSM), cardiotrophin-1, and IL-11. Functioning in a pleiotropic and redundant manner, these cytokines play an important role in the regulation of complex cellular processes such as gene activation, proliferation and differentiation, by signalling through homo- or heterodimers of gp130.
This thesis describes the characterization of the interactions between t...Expand abstract
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- University of Oxford
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- Jiejin Li
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- This thesis was digitised thanks to the generosity of Dr Leonard Polonsky.
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