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Low frequency lung resistance is a global bronchoconstriction detection measure, but is still sensitive to small airways disease

Abstract:
The Forced Oscillation Technique (FOT) is experiencing increased uptake as a clinical measure of lung function and airway constriction. However, due to the complex nature of test outputs, there is still uncertainty about exactly how test indices from the FOT respond to specific types of lung disease, such as bronchoconstriction and tissue breakdown. By comparing correlations of clinical and simulated data, we provide evidence of the nature of these responses.
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Institution:
University of Oxford
Division:
MPLS Division
Department:
Computer Science
Oxford college:
New College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS Division
Department:
Computer Science
Role:
Author
Rhodes Trust More from this funder
Sir Jules Thorn Trust More from this funder
Roche Pharmaceuticals More from this funder
National Institute for Health Research More from this funder
Seventh Framework Programme More from this funder
Publisher:
American Thoracic Society Publisher's website
Publication date:
2018-05-23
Acceptance date:
2018-01-22
Pubs id:
pubs:840496
URN:
uri:a5d772c8-d50d-42aa-b257-fcb83d07449a
UUID:
uuid:a5d772c8-d50d-42aa-b257-fcb83d07449a
Local pid:
pubs:840496

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